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Further studies involving robust mechanistic validation, pharmacokinetic profiling, and clinical translation are essential to determine whether these compounds possess genuine therapeutic potential or if their effects are limited to experimental settings

The capacity for GSH synthesis is insufficient to maintain GSH concentrations when tissues are exposed to certain drugs or their metabolites (e.g., acetaminophen), redox cycling compounds (e.g., menadione), peroxides (e.g., tertbutyl hydroperoxide), X-rays, or ultraviolet radiation

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[DOI] [PubMed] [Google Scholar] 22.Bauwe H., Hagemann M., Kern R., Timm S

Still, they differ in structural origin and primary research focus